BDBM652651 6-N-({2-[(1-methylpiperidin-4-yl)methoxy]-6-(trifluoromethyl)pyridin-4- yl}methyl)isoquinoline-1,6-diamine::US20240059691, Example 4265
SMILES CN1CCC(COc2cc(CNc3ccc4c(N)nccc4c3)cc(n2)C(F)(F)F)CC1
InChI Key InChIKey=RETOSFBTHJWCPW-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 652651
Affinity DataIC50: 200nMAssay Description:In vitro inhibition of Factor XIIa was determined using an IC50 assay based on standard literature methods (see e.g Baeriswyl et al., ACS Chem. Biol....More data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair