BDBM652665 (5S)-5-{[(4-{[(1-aminoisoquinolin-5-yl)amino]methyl}pyridin-2-yl)oxy]methyl}-3-methyl- 1,3-oxazolidin-2-one::US20240059691, Example 4279
SMILES CN1C[C@@H](COc2cc(CNc3cccc4c(N)nccc34)ccn2)OC1=O
InChI Key InChIKey=JIRZTKNHLRBCKF-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 652665
Affinity DataIC50: 6.50E+3nMAssay Description:In vitro inhibition of Factor XIIa was determined using an IC50 assay based on standard literature methods (see e.g Baeriswyl et al., ACS Chem. Biol....More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+4nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+4nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+4nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair