BDBM652704 N5-methyl-N5-((2-((1-methylpiperidin-4-yl)methoxy)pyridin-4-yl)methyl)isoquinoline- 1,5-diamine::US20240059691, Example 4419

SMILES CN(Cc1ccnc(OCC2CCN(C)CC2)c1)c1cccc2c(N)nccc12

InChI Key InChIKey=HRTOIBPNAUKSTE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 652704   

TargetCoagulation factor XII(Human)
Kalvista Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 652704BDBM652704(US20240059691, Example 4419 | N5-methyl-N5-((2-((1...)
Affinity DataIC50: 6.50E+3nMAssay Description:In vitro inhibition of Factor XIIa was determined using an IC50 assay based on standard literature methods (see e.g Baeriswyl et al., ACS Chem. Biol....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent