BDBM652778 N3,N3-dimethyl-N6-((6-(((1-methylpiperidin-4-yl)methyl)amino)pyridin-3- yl)methyl)pyridazine-3,6-diamine::US20240059691, Example 1186

SMILES CN(C)c1ccc(NCc2ccc(NCC3CCN(C)CC3)nc2)nn1

InChI Key InChIKey=DFGACCKQXURGBX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 652778   

TargetPlasma kallikrein(Human)
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652778(US20240059691, Example 1186 | N3,N3-dimethyl-N6-((...)
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent