BDBM653610 N-(5-phenylisoxazol-3- yl)cyclohexanesulfonamide::US11911372, Example 31::US20240277683, Example 31

SMILES O=S(=O)(Nc1cc(on1)-c1ccccc1)C1CCCCC1

InChI Key InChIKey=VRCACJKGCIGKCY-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 653610   

TargetHistone acetyltransferase KAT7 [325-611](Human)
CTXT PTY

US Patent
LigandChemical structure of BindingDB Monomer ID 653610BDBM653610(N-(5-phenylisoxazol-3- yl)cyclohexanesulfonamide |...)
Affinity DataIC50: 2.24E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT7 [325-611](Human)
CTXT PTY

US Patent
LigandChemical structure of BindingDB Monomer ID 653610BDBM653610(N-(5-phenylisoxazol-3- yl)cyclohexanesulfonamide |...)
Affinity DataIC50: 2.24E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A [507-778](Human)
CTXT PTY

US Patent
LigandChemical structure of BindingDB Monomer ID 653610BDBM653610(N-(5-phenylisoxazol-3- yl)cyclohexanesulfonamide |...)
Affinity DataIC50: 2.51E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A [507-778](Human)
CTXT PTY

US Patent
LigandChemical structure of BindingDB Monomer ID 653610BDBM653610(N-(5-phenylisoxazol-3- yl)cyclohexanesulfonamide |...)
Affinity DataIC50: 2.51E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT8 [177-447](Human)
CTXT PTY

US Patent
LigandChemical structure of BindingDB Monomer ID 653610BDBM653610(N-(5-phenylisoxazol-3- yl)cyclohexanesulfonamide |...)
Affinity DataIC50: 5.03E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT8 [177-447](Human)
CTXT PTY

US Patent
LigandChemical structure of BindingDB Monomer ID 653610BDBM653610(N-(5-phenylisoxazol-3- yl)cyclohexanesulfonamide |...)
Affinity DataIC50: 5.03E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 653610BDBM653610(N-(5-phenylisoxazol-3- yl)cyclohexanesulfonamide |...)
Affinity DataIC50: 8.79E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 653610BDBM653610(N-(5-phenylisoxazol-3- yl)cyclohexanesulfonamide |...)
Affinity DataIC50: 8.79E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent