BDBM653618 3,4-dimethyl-N-(5- phenylisoxazol-3- yl)benzenesulfonamide::US11911372, Example 40::US20240277683, Example 40

SMILES Cc1ccc(cc1C)S(=O)(=O)Nc1cc(on1)-c1ccccc1

InChI Key InChIKey=YTJMCHAZVQNPSU-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 653618   

LigandChemical structure of BindingDB Monomer ID 653618BDBM653618(3,4-dimethyl-N-(5- phenylisoxazol-3- yl)benzenesul...)
Affinity DataIC50: 3.97E+3nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 653618BDBM653618(3,4-dimethyl-N-(5- phenylisoxazol-3- yl)benzenesul...)
Affinity DataIC50: 3.97E+3nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT7(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 653618BDBM653618(3,4-dimethyl-N-(5- phenylisoxazol-3- yl)benzenesul...)
Affinity DataIC50: 1.56E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT7(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 653618BDBM653618(3,4-dimethyl-N-(5- phenylisoxazol-3- yl)benzenesul...)
Affinity DataIC50: 1.56E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT8 [177-447](Human)
CTXT PTY

US Patent
LigandChemical structure of BindingDB Monomer ID 653618BDBM653618(3,4-dimethyl-N-(5- phenylisoxazol-3- yl)benzenesul...)
Affinity DataIC50: 2.63E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT8 [177-447](Human)
CTXT PTY

US Patent
LigandChemical structure of BindingDB Monomer ID 653618BDBM653618(3,4-dimethyl-N-(5- phenylisoxazol-3- yl)benzenesul...)
Affinity DataIC50: 2.63E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 653618BDBM653618(3,4-dimethyl-N-(5- phenylisoxazol-3- yl)benzenesul...)
Affinity DataIC50: 2.90E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 653618BDBM653618(3,4-dimethyl-N-(5- phenylisoxazol-3- yl)benzenesul...)
Affinity DataIC50: 2.90E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent