BDBM653621 4-fluoro-N-(5-phenylisoxazol-3- yl)benzenesulfonamide::US11911372, Example 43::US20240277683, Example 43

SMILES Fc1ccc(cc1)S(=O)(=O)Nc1cc(on1)-c1ccccc1

InChI Key InChIKey=HCGQPWVXCATVAE-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 653621   

TargetHistone acetyltransferase KAT7(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 653621BDBM653621(4-fluoro-N-(5-phenylisoxazol-3- yl)benzenesulfonam...)
Affinity DataIC50: 2.52E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT7(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 653621BDBM653621(4-fluoro-N-(5-phenylisoxazol-3- yl)benzenesulfonam...)
Affinity DataIC50: 2.52E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 653621BDBM653621(4-fluoro-N-(5-phenylisoxazol-3- yl)benzenesulfonam...)
Affinity DataIC50: 3.67E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 653621BDBM653621(4-fluoro-N-(5-phenylisoxazol-3- yl)benzenesulfonam...)
Affinity DataIC50: 3.67E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 653621BDBM653621(4-fluoro-N-(5-phenylisoxazol-3- yl)benzenesulfonam...)
Affinity DataIC50: 8.64E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 653621BDBM653621(4-fluoro-N-(5-phenylisoxazol-3- yl)benzenesulfonam...)
Affinity DataIC50: 8.64E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent