BDBM653623 4-cyano-N-(5-phenylisoxazol-3- yl)benzenesulfonamide::US11911372, Example 45::US20240277683, Example 45

SMILES O=S(=O)(Nc1cc(on1)-c1ccccc1)c1ccc(cc1)C#N

InChI Key InChIKey=AZYWPVPKDHQRBQ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 653623   

TargetHistone acetyltransferase KAT6A [507-778](Human)
CTXT PTY

US Patent
LigandChemical structure of BindingDB Monomer ID 653623BDBM653623(4-cyano-N-(5-phenylisoxazol-3- yl)benzenesulfonami...)
Affinity DataIC50: 4.87E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A [507-778](Human)
CTXT PTY

US Patent
LigandChemical structure of BindingDB Monomer ID 653623BDBM653623(4-cyano-N-(5-phenylisoxazol-3- yl)benzenesulfonami...)
Affinity DataIC50: 4.87E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT7 [325-611](Human)
CTXT PTY

US Patent
LigandChemical structure of BindingDB Monomer ID 653623BDBM653623(4-cyano-N-(5-phenylisoxazol-3- yl)benzenesulfonami...)
Affinity DataIC50: 1.23E+5nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT7 [325-611](Human)
CTXT PTY

US Patent
LigandChemical structure of BindingDB Monomer ID 653623BDBM653623(4-cyano-N-(5-phenylisoxazol-3- yl)benzenesulfonami...)
Affinity DataIC50: 1.23E+5nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 653623BDBM653623(4-cyano-N-(5-phenylisoxazol-3- yl)benzenesulfonami...)
Affinity DataIC50: 1.25E+5nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT8(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 653623BDBM653623(4-cyano-N-(5-phenylisoxazol-3- yl)benzenesulfonami...)
Affinity DataIC50: 1.25E+5nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 653623BDBM653623(4-cyano-N-(5-phenylisoxazol-3- yl)benzenesulfonami...)
Affinity DataIC50: 1.25E+5nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT8(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 653623BDBM653623(4-cyano-N-(5-phenylisoxazol-3- yl)benzenesulfonami...)
Affinity DataIC50: 1.25E+5nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent