BDBM653631 5-ethyl-2-methoxy-N-(5-phenyl- 1,2,4-oxadiazol-3- yl)benzenesulfonamide::US11911372, Example 53::US20240277683, Example 53

SMILES CCc1ccc(OC)c(c1)S(=O)(=O)Nc1noc(n1)-c1ccccc1

InChI Key InChIKey=QJQWYKYAOUHMLT-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 653631   

LigandChemical structure of BindingDB Monomer ID 653631BDBM653631(5-ethyl-2-methoxy-N-(5-phenyl- 1,2,4-oxadiazol-3- ...)
Affinity DataIC50: 1.27E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 653631BDBM653631(5-ethyl-2-methoxy-N-(5-phenyl- 1,2,4-oxadiazol-3- ...)
Affinity DataIC50: 1.27E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT7(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 653631BDBM653631(5-ethyl-2-methoxy-N-(5-phenyl- 1,2,4-oxadiazol-3- ...)
Affinity DataIC50: 1.92E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT7(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 653631BDBM653631(5-ethyl-2-methoxy-N-(5-phenyl- 1,2,4-oxadiazol-3- ...)
Affinity DataIC50: 1.92E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 653631BDBM653631(5-ethyl-2-methoxy-N-(5-phenyl- 1,2,4-oxadiazol-3- ...)
Affinity DataIC50: 5.48E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 653631BDBM653631(5-ethyl-2-methoxy-N-(5-phenyl- 1,2,4-oxadiazol-3- ...)
Affinity DataIC50: 5.48E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent