BDBM653654 N-(5-phenylisoxazol-3-yl)- 5,6,7,8- tetrahydronaphthalene-2- sulfonamide::US11911372, Example 76::US20240277683, Example 76

SMILES O=S(=O)(Nc1cc(on1)-c1ccccc1)c1ccc2CCCCc2c1

InChI Key InChIKey=JCXPRXUBBBUVER-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 653654   

LigandChemical structure of BindingDB Monomer ID 653654BDBM653654(N-(5-phenylisoxazol-3-yl)- 5,6,7,8- tetrahydronaph...)
Affinity DataIC50: 9.12E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 653654BDBM653654(N-(5-phenylisoxazol-3-yl)- 5,6,7,8- tetrahydronaph...)
Affinity DataIC50: 9.12E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 653654BDBM653654(N-(5-phenylisoxazol-3-yl)- 5,6,7,8- tetrahydronaph...)
Affinity DataIC50: 1.25E+5nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 653654BDBM653654(N-(5-phenylisoxazol-3-yl)- 5,6,7,8- tetrahydronaph...)
Affinity DataIC50: 1.25E+5nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent