BDBM653658 US11911372, Example 80::US20240277683, Example 80

SMILES Brc1cccc(c1)-c1cc(NS(=O)(=O)c2ccccc2)on1

InChI Key InChIKey=CGIXLOMAZYZHSZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 653658   

TargetHistone acetyltransferase KAT6A [507-778](Human)
CTXT PTY

US Patent
LigandChemical structure of BindingDB Monomer ID 653658BDBM653658(US11911372, Example 80 | US20240277683, Example 80)
Affinity DataIC50: 1.48E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A [507-778](Human)
CTXT PTY

US Patent
LigandChemical structure of BindingDB Monomer ID 653658BDBM653658(US11911372, Example 80 | US20240277683, Example 80)
Affinity DataIC50: 1.48E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 653658BDBM653658(US11911372, Example 80 | US20240277683, Example 80)
Affinity DataIC50: 2.66E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 653658BDBM653658(US11911372, Example 80 | US20240277683, Example 80)
Affinity DataIC50: 2.66E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT7 [325-611](Human)
CTXT PTY

US Patent
LigandChemical structure of BindingDB Monomer ID 653658BDBM653658(US11911372, Example 80 | US20240277683, Example 80)
Affinity DataIC50: 2.70E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT7 [325-611](Human)
CTXT PTY

US Patent
LigandChemical structure of BindingDB Monomer ID 653658BDBM653658(US11911372, Example 80 | US20240277683, Example 80)
Affinity DataIC50: 2.70E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent