BDBM653670 US11911372, Example 93::US20240277683, Example 93

SMILES COc1cccc(OC)c1S(=O)(=O)Nc1cc(on1)-c1ccccc1

InChI Key InChIKey=PRLUVSGBYSXNGY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 653670   

LigandPNGBDBM653670(US11911372, Example 93 | US20240277683, Example 93)
Affinity DataIC50: 8.12E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT6A [507-778](Human)
CTXT PTY

US Patent
LigandPNGBDBM653670(US11911372, Example 93 | US20240277683, Example 93)
Affinity DataIC50: 2.16E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT7 [325-611](Human)
CTXT PTY

US Patent
LigandPNGBDBM653670(US11911372, Example 93 | US20240277683, Example 93)
Affinity DataIC50: 4.58E+3nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
Go to US Patent

LigandPNGBDBM653670(US11911372, Example 93 | US20240277683, Example 93)
Affinity DataIC50: 8.12E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT6A [507-778](Human)
CTXT PTY

US Patent
LigandPNGBDBM653670(US11911372, Example 93 | US20240277683, Example 93)
Affinity DataIC50: 2.16E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT7 [325-611](Human)
CTXT PTY

US Patent
LigandPNGBDBM653670(US11911372, Example 93 | US20240277683, Example 93)
Affinity DataIC50: 4.58E+3nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent