BDBM653677 US11911372, Example 100::US20240277683, Example 100

SMILES COc1ccc(cc1-c1nnc(NS(=O)(=O)c2c(OC)cccc2OC)s1)C(F)(F)F

InChI Key InChIKey=RGYKWDDLAMPYAZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 653677   

LigandChemical structure of BindingDB Monomer ID 653677BDBM653677(US11911372, Example 100 | US20240277683, Example 1...)
Affinity DataIC50: 931nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 653677BDBM653677(US11911372, Example 100 | US20240277683, Example 1...)
Affinity DataIC50: 931nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT7(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 653677BDBM653677(US11911372, Example 100 | US20240277683, Example 1...)
Affinity DataIC50: 2.85E+3nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT7(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 653677BDBM653677(US11911372, Example 100 | US20240277683, Example 1...)
Affinity DataIC50: 2.85E+3nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 653677BDBM653677(US11911372, Example 100 | US20240277683, Example 1...)
Affinity DataIC50: 1.12E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 653677BDBM653677(US11911372, Example 100 | US20240277683, Example 1...)
Affinity DataIC50: 1.12E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent