BDBM653703 US11911372, Example 126::US20240277683, Example 126

SMILES CCc1ccc(OC)c(c1)S(=O)(=O)Nc1nnc(o1)-c1ccccc1

InChI Key InChIKey=RCLKEQDYQCLOFY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 653703   

TargetHistone acetyltransferase KAT7 [325-611](Human)
CTXT PTY

US Patent
LigandChemical structure of BindingDB Monomer ID 653703BDBM653703(US11911372, Example 126 | US20240277683, Example 1...)
Affinity DataIC50: 7.45E+3nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT7 [325-611](Human)
CTXT PTY

US Patent
LigandChemical structure of BindingDB Monomer ID 653703BDBM653703(US11911372, Example 126 | US20240277683, Example 1...)
Affinity DataIC50: 7.45E+3nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A [507-778](Human)
CTXT PTY

US Patent
LigandChemical structure of BindingDB Monomer ID 653703BDBM653703(US11911372, Example 126 | US20240277683, Example 1...)
Affinity DataIC50: 9.40E+3nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A [507-778](Human)
CTXT PTY

US Patent
LigandChemical structure of BindingDB Monomer ID 653703BDBM653703(US11911372, Example 126 | US20240277683, Example 1...)
Affinity DataIC50: 9.40E+3nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 653703BDBM653703(US11911372, Example 126 | US20240277683, Example 1...)
Affinity DataIC50: 1.46E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 653703BDBM653703(US11911372, Example 126 | US20240277683, Example 1...)
Affinity DataIC50: 1.46E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent