BDBM655786 (R)-2-acetamido-4-((1-(4-(6-(6-(2-(3-fluorophenyl) pyrrolidin-1-yl)imidazo[1,2-b]pyridazin-3-yl)pyridin-2-yl)piperazin-1-yl)-2-oxo-6,9,12,15-tetraoxa-3-azaheptadecan-17-yl)amino)-N-(4-methyl-5-nitrothiazol-2-yl)benzamide::US20240066136,Compound D-23

SMILES CC(=O)Nc1cc(NCCOCCOCCOCCOCCNC(=O)CN2CCN(CC2)c2cccc(n2)-c2cnc3ccc(nn23)N2CCC[C@@H]2c2cccc(F)c2)ccc1C(=O)Nc1nc(C)c(s1)[N+]([O-])=O

InChI Key InChIKey=DVYFQRWHMXLACB-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 655786   

TargetDNA damage-binding protein 1(Human)
Cullgen (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 655786BDBM655786(US20240066136,Compound D-23 | (R)-2-acetamido-4-((...)
Affinity DataKd:  6.00E+4nMAssay Description:Surface plasmon resonance (SPR) binding assay. All SPR studies were performed on a Biacore X100 plus or T200 instrument (GE Healthcare). Immobilizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent