BDBM656734 N-{[(3R,6S)-6-{[2-(5-{2-[(3R,5R)-3,5- Dimethylmorpholine-4-carbonyl]-4- fluorophenoxy}pyrimidin-4-yl)-2,7- diazaspiro[3.5]nonan-7-yl]methyl}oxan-3- yl]sulfamoyl}-N-methylcyclopropanamine::US11919901, Compound 129

SMILES C[C@@H]1COC[C@@H](C)N1C(=O)c1cc(F)ccc1Oc1cncnc1N1CC2(C1)CCN(C[C@@H]1CC[C@H](CO1)NS(=O)(=O)N(C)C1CC1)CC2

InChI Key InChIKey=BBLLYMLVTMCREX-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 656734   

TargetHistone-lysine N-methyltransferase 2A/Menin(Human)
Syndax Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 656734BDBM656734(N-{[(3R,6S)-6-{[2-(5-{2-[(3R,5R)-3,5- Dimethylmorp...)
Affinity DataKi: <1nMAssay Description:Table 4: For Ki determination, individual compounds were prepared as 10 mM DMSO stock solutions. Considering DMSO as the vehicle in the assay system....More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2024
Entry Details
US Patent