BDBM656831 2-((4-(7-(((2S,5R)-5-((R)- Ethylsulfonoamidimidamido)tetrahydro-2H-pyran- 2-yl)methyl)-2,7-diazaspiro[3.5]nonan-2- yl)pyrimidin-5-yl)oxy)-5-fluoro-N,N- diisopropylbenzamide::US11919901, Compound 227

SMILES CC[S@](=N)(=O)N[C@@H]1CC[C@@H](CN2CCC3(CN(C3)c3ncncc3Oc3ccc(F)cc3C(=O)N(C(C)C)C(C)C)CC2)OC1

InChI Key InChIKey=FWTQLKNKXQFTRF-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 656831   

TargetHistone-lysine N-methyltransferase 2A/Menin(Human)
Syndax Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 656831BDBM656831(2-((4-(7-(((2S,5R)-5-((R)- Ethylsulfonoamidimidami...)
Affinity DataKi: <1nMAssay Description:Table 4: For Ki determination, individual compounds were prepared as 10 mM DMSO stock solutions. Considering DMSO as the vehicle in the assay system....More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2024
Entry Details
US Patent