BDBM662969 US20240109879, Compound 4A

SMILES CO[C@H]1CCC(CC1)n1c(nc2cc(ccc12)-c1c(C)noc1C)[C@@H]1CN(C)C(=O)N1c1ccc(F)c(F)c1

InChI Key InChIKey=YMVDJIIWWCHTGJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 662969   

TargetHistone acetyltransferase p300(Human)
Medshine Discovery

US Patent
LigandPNGBDBM662969(US20240109879, Compound 4A)
Affinity DataIC50: 11.3nMAssay Description:Reagent:Reaction buffer: 25 mM HEPES, pH 7.5, 25 mM NaCl, 0.025% CHAPS, 0.025% BSA, 0.5% DMSO.Ligand:Histone H4 (1-21) K5/8/12/16Ac-GG-Biotin.Standar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent