BDBM663560 ((1S,6R,7R)-3-(6-((3-chloro-2-(1H-pyrazol-1- yl)pyridin-4-yl)thio)pyrido[2,3-b]pyrazin-2-yl)-7-(2- fluorophenyl)-3-azabicyclo[4.1.0]heptan-7- yl)methanamine::US20240109900, Example 398

SMILES CC[C@@]1(C2CCN(CC12)c1cnc2nc(Cc3ccnc(c3C)-n3cccn3)ccc2n1)c1ccccc1F

InChI Key InChIKey=ZEGRGIZAUSKVRH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 663560   

LigandPNGBDBM663560(((1S,6R,7R)-3-(6-((3-chloro-2-(1H-pyrazol-1- yl)py...)
Affinity DataIC50: 500nMAssay Description:Assay volume of 20 μL/well was assembled in 384 well black polystyrene low-binding microplates (Greiner), using the following buffer: 60 mM HEPE...More data for this Ligand-Target Pair
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Date in BDB:
6/20/2024
Entry Details
US Patent