BDBM663644 ((1R,5S,6r)-6-(4-methylthiazol-2-yl)-3-(3- (pyrazolo[1,5-a]pyridin-4-yl)-1H-pyrazolo[3,4- b]pyrazin-6-yl)-3-azabicyclo[3.1.0]hexan-6- yl)methanamine::US20240109900, Example 482

SMILES Cc1csc(n1)[C@]1(CN)[C@H]2CN(C[C@@H]12)c1cnc2c(n[nH]c2n1)-c1cccn2nccc12

InChI Key InChIKey=FEHUNTAWTYHEOF-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 663644   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
IRBM

US Patent

LigandBDBM663644(((1R,5S,6r)-6-(4-methylthiazol-2-yl)-3-(3- (pyrazo...)Copy SMILESCopy InChI

Affinity DataIC50: 500nMAssay Description:Assay volume of 20 μL/well was assembled in 384 well black polystyrene low-binding microplates (Greiner), using the following buffer: 60 mM HEPE...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/20/2024
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL