BDBM665608 5-[[(5-chloro-3-pyridyl)-methyl-amino]methyl]-N-[(1S)-1-(cyclohexyl methyl)-2-[[4-(dimethylamino)cyclohexyl]amino]-2-oxo-ethyl]thiophene-2-carboxamide::US20240116910, Compound 298

SMILES CN(C)C1CCC(CC1)NC(=O)[C@H](CC1CCCCC1)NC(=O)c1ccc(CN(C)c2cncc(Cl)c2)s1

InChI Key InChIKey=QFOBALPMHQAKJZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 665608   

TargetProtein phosphatase 1D(Human)
PMV Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665608(US20240116910, Compound 298 | 5-[[(5-chloro-3-pyri...)
Affinity DataIC50: 11nMAssay Description:Test compounds (252 mM stock in DMSO) were diluted 3 folds in series in DMSO and 1.2 μl per well were added into 384-well polypropylene black pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetProtein phosphatase 1D [2-420](Human)
PMV Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665608(US20240116910, Compound 298 | 5-[[(5-chloro-3-pyri...)
Affinity DataIC50: 31nMAssay Description:Test compounds (252 mM stock in DMSO) were diluted 3 folds in series in DMSO and 1.2 μl per well were added into 384-well polypropylene black pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent