BDBM672874 Example 4A 1″-methyldispiro[1,3-dioxolane-2,1′-cyclohexane-4′,3″-indole]-2″-one::US20240150293, Example 4

SMILES CN1CC2(CCC(CC2)(Nc2cccc(Br)c2)C(O)=O)c2ccccc12

InChI Key InChIKey=KNOJGCJEXLVDIQ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 672874   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
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US Patent
LigandPNGBDBM672874(US20240150293, Example 4 | Example 4A 1″-met...)
Affinity DataKi:  5.95E+3nMAssay Description:The relative binding potency of each compound was determined via Fluorescence Polarisation (FP). The method utilised a Fluorescein labelled ligand (F...More data for this Ligand-Target Pair
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Date in BDB:
8/9/2024
Entry Details
US Patent