BDBM673064 (1r,4r)-4-(3-chloroanilino)-2′-[2-(pyridin-2-yl)ethyl]spiro[cyclohexane-1,1′-indene]-4-carboxylic acid::US20240150293, Example 199

SMILES OC(=O)[C@]1(CC[C@@]2(CC1)C(CCc1ccccn1)Cc1ccccc21)Nc1cccc(Cl)c1

InChI Key InChIKey=MZKFVXGMHWFZGT-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 673064   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
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US Patent
LigandPNGBDBM673064(US20240150293, Example 199 | (1r,4r)-4-(3-chloroan...)
Affinity DataKi:  1.25E+3nMAssay Description:The addition of a compound which binds competitively to the same site as the peptide will result in an increase in the fluorescence intensity of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent