BDBM673163 (1s,4s)-4-(3-chloroanilino)-2′-(4-chlorophenyl)spiro[cyclohexane-1,1′-indene]-4-carboxylic acid::US20240150293, Example 298

SMILES OC(=O)[C@H]1CC[C@@]2(CC1Nc1cccc(Cl)c1)C(=Cc1ccccc21)c1ccc(Cl)cc1

InChI Key InChIKey=DGZOGKKJIFAJGP-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 673163   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
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US Patent
LigandPNGBDBM673163(US20240150293, Example 298 | (1s,4s)-4-(3-chloroan...)
Affinity DataKi:  1.11E+3nMAssay Description:The relative binding potency of each compound was determined via Fluorescence Polarisation (FP). The method utilised a Fluorescein labelled ligand (F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent