BDBM673343 (1r,2′S,4S)-4-(3-chloroanilino)-2′-{3-[(5-methyl-1H-indol-4-yl)oxy]propyl}-2′,3′-dihydrospiro[cyclohexane-1,1′-indene]-4-carboxylic acid::US20240150293, Example 490

SMILES Cc1ccc2[nH]ccc2c1OCCC[C@H]1Cc2ccccc2[C@@]11CC[C@](CC1)(Nc1cccc(Cl)c1)C(O)=O

InChI Key InChIKey=BRBANBRINJHBGI-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 673343   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
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US Patent
LigandPNGBDBM673343(US20240150293, Example 490 | (1r,2′S,4S)-4-(...)
Affinity DataKi:  61.8nMAssay Description:The addition of a compound which binds competitively to the same site as the peptide will result in an increase in the fluorescence intensity of the ...More data for this Ligand-Target Pair
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Date in BDB:
8/9/2024
Entry Details
US Patent