BDBM673683 (1r,2′R,4R)-4-(3-chloroanilino)-6′-(hydroxymethyl)-2′-[(2R)-2-methyl-3-{[(5R)-5-methyl-5,6,7,8-tetrahydroquinolin-4-yl]oxy}propyl]-2′,3′-dihydrospiro[cyclohexane-1,1′-indene]-4-carboxylic acid::US20240150293, Example 869::US20240150293, Example 870

SMILES C[C@@H](COc1ccnc2CCC[C@@H](C)c12)CC1=Cc2ccc(CO)cc2[C@@]11CC[C@](CC1)(Nc1cccc(Cl)c1)C(O)=O

InChI Key InChIKey=RIAHULCOONKSFW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 673683   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Les Laboratoires Servier

US Patent
LigandPNGBDBM673683(US20240150293, Example 869 | (1r,2′R,4R)-4-(...)
Affinity DataKi:  0.0510nMAssay Description:The addition of a compound which binds competitively to the same site as the peptide will result in an increase in the fluorescence intensity of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Les Laboratoires Servier

US Patent
LigandPNGBDBM673683(US20240150293, Example 869 | (1r,2′R,4R)-4-(...)
Affinity DataKi:  0.384nMAssay Description:The addition of a compound which binds competitively to the same site as the peptide will result in an increase in the fluorescence intensity of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent