BDBM676548 PF-03531814::US20240166643, Comparative Example 1

SMILES CN(C)CCNc1ncc(Cl)c(n1)N1CC(C1)C(=O)NCc1cnc(C)cn1

InChI Key InChIKey=MOFCMEPDMSMSFS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 676548   

TargetGlycylpeptide N-tetradecanoyltransferase(malaria parasite P. vivax)
Imperial College Innovations

US Patent
LigandPNGBDBM676548(PF-03531814 | US20240166643, Comparative Example 1)
Affinity DataIC50: 8.40nMAssay Description:The IC50 values of certain Example Compounds of the invention, and for Comparative Examples 1 and 2, for Human NMT1 (HsNMT1) and Plasmodium vivax (Pv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGlycylpeptide N-tetradecanoyltransferase 1(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM676548(PF-03531814 | US20240166643, Comparative Example 1)
Affinity DataIC50: 46nMAssay Description:The IC50 values of certain Example Compounds of the invention, and for Comparative Examples 1 and 2, for Human NMT1 (HsNMT1) and Plasmodium vivax (Pv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent