BDBM676766 US20240166651, Example 7::ethyl 7-((1-(4-cyano-3-fluorophenyl)pyrrolidin-3-

SMILES CCOC(=O)c1cnc2ccsc2c1NC1CCN(C1)c1ccc(C#N)c(F)c1

InChI Key InChIKey=SBNUKJOFELIPEI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 676766   

TargetTyrosine-protein kinase JAK1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM676766(ethyl 7-((1-(4-cyano-3-fluorophenyl)pyrrolidin-3- ...)
Affinity DataIC50: 1.00E+3nMAssay Description:The objective of this study was to assess the activity of novel JAK inhibitors measuring the capability of compounds to inhibit JAK1 kinase activity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent