BDBM677275 N2-(1-tert-butylindazol-4-yl)-N4-cyclopropyl-5-(trifluoromethyl)pyrimidine-2,4-diamine::US20240174647, Example 196

SMILES CC(C)(C)n1ncc2c(Nc3ncc(c(NC4CC4)n3)C(F)(F)F)cccc12

InChI Key InChIKey=KPMFNSPHUAVRQC-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 677275   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Neuron23

US Patent

LigandBDBM677275(US20240174647, Example 196 | N2-(1-tert-butylindaz...)Copy SMILESCopy InChI

Affinity DataIC50: 50nMAssay Description:The protocol for basic TR-FRET LanthaScreen Tb Kinase Activity Assay inhibitor studies were as follows. LanthaScreen Kinase Activity Assays (ThermoFi...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/5/2024
Entry Details
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