BDBM680054 5-{6-[2-(6-Fluoro-2,4-dimethyl-indol-1-yl)-ethylamino]-pyrimidin-4-yl}-3- trifluoromethyl-thiophene-2-carboxylic acid::US12011444, Example 269

SMILES Cc1cc2c(C)cc(F)cc2n1CCNc1cc(ncn1)-c1cc(c(s1)C(O)=O)C(F)(F)F

InChI Key InChIKey=LOVGYRGYKSVLIN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 680054   

TargetProstaglandin E2 receptor EP2 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM680054(US12011444, Example 269 | 5-{6-[2-(6-Fluoro-2,4-di...)
Affinity DataIC50: 61nMAssay Description:Stock solutions of test compounds are made at a concentration of 10 mM in DMSO, and serially diluted in DMSO to concentrations required for inhibitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM680054(US12011444, Example 269 | 5-{6-[2-(6-Fluoro-2,4-di...)
Affinity DataIC50: 117nMAssay Description:Stock solutions of test compounds are made at a concentration of 10 mM in DMSO, and serially diluted in DMSO to concentrations required for inhibitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
US Patent