BDBM680083 US12011444, Example 298::{6-[4-(2-Amino-5-methyl-thiazol-4-yl)-phenyl]-pyrimidin-4-yl}-[2-(7-fluoro-2,4-dimethyl- indol-1-yl)-ethyl]-amine

SMILES Cc1cc2c(C)ccc(F)c2n1CCNc1cc(ncn1)-c1ccc(cc1)-c1nc(N)sc1C

InChI Key InChIKey=CBSWBXWUJBGLMO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 680083   

TargetProstaglandin E2 receptor EP2 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM680083(US12011444, Example 298 | {6-[4-(2-Amino-5-methyl-...)
Affinity DataIC50: 19nMAssay Description:Stock solutions of test compounds are made at a concentration of 10 mM in DMSO, and serially diluted in DMSO to concentrations required for inhibitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM680083(US12011444, Example 298 | {6-[4-(2-Amino-5-methyl-...)
Affinity DataIC50: 249nMAssay Description:Stock solutions of test compounds are made at a concentration of 10 mM in DMSO, and serially diluted in DMSO to concentrations required for inhibitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
US Patent