BDBM682166 8-(6-((R)-1-(2-(4- fluoropiperidin-1- yl)ethoxy)ethyl)pyridin-3-yl)- 3-methyl-1-(tetrahydro-2H- pyran-4-yl)-1,3,3a,9b- tetrahydro-2H-imidazo[4,5- c]cinnolin-2-one::US20240207263, Example 108

SMILES C[C@@H](OCCN1CCC(F)CC1)c1ccc(cn1)-c1ccc2nnc3n(C)c(=O)n(C4CCOCC4)c3c2c1

InChI Key InChIKey=NOIKYWREOBBEMK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 682166   

TargetSerine-protein kinase ATM(Human)
Suzhou Zanrong Pharma

US Patent
LigandPNGBDBM682166(US20240207263, Example 108 | 8-(6-((R)-1-(2-(4- fl...)
Affinity DataIC50: 3.70nMAssay Description:ATM (Millipore, Cat. No. 14-933) enzyme solution was prepared in 1x kinase base buffer. 10 ul of 2x enzyme solution was transferred to each well of t...More data for this Ligand-Target Pair
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Date in BDB:
10/4/2024
Entry Details
US Patent