BDBM683064 Preparation of 4-(5-(3-amino-8-azabicyclo[3.2.1]octane-8-carbonyl)-2-(5-fluoro-3-pentylbenzo[d]isoxazol-6-yl) thiophen-3-yl)-2-fluorobenzonitrile::US20240216357, Example 8

SMILES CCCCCc1noc2cc(-c3sc(cc3-c3ccc(C#N)c(F)c3)C(=O)N3C4CCC3CC(N)C4)c(F)cc12

InChI Key InChIKey=AZGJPBYEFBKPLT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 683064   

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical

US Patent
LigandPNGBDBM683064(US20240216357, Example 8 | Preparation of 4-(5-(3-...)
Affinity DataIC50: 0.300nMAssay Description:The effects of compounds on LSD1 enzyme activity are detected by an HTRF technology to evaluate their inhibition levels on LSD1 enzyme activity. Firs...More data for this Ligand-Target Pair
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Date in BDB:
10/11/2024
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