BDBM684488 US20240218021, Example 341

SMILES CC(C)C[C@@H]1NC(=O)[C@H](CCCCNC(=O)[C@H]2C[C@@H](F)CN2C(=O)[C@H](Cc2cc(Cl)ccc2Cl)N(C)C1=O)N(C)C(=O)[C@@H](NC(=O)[C@@H]1C[C@@H](F)CN1C(=O)C1(CC1)C(F)(F)F)C1CCC1

InChI Key InChIKey=BOFAUXDTFWMQDS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 684488   

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Circle Pharma

US Patent
LigandPNGBDBM684488(US20240218021, Example 341)
Affinity DataIC50: 280nMAssay Description:FP binding assays were performed in 25 mM HEPES pH 7.5, 100 mM NaCl, 1 mM DTT, 0.01% NP-40 and 1 mg/mL BSA for all 3 protein complexes in black 96-we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2024
Entry Details
US Patent