BDBM685115 US12037345, Example 196::rac-5-(4- chloro-2- ethyl-2H- indazol-5-yl)- 2-{2,6-diaza- spiro[3.4] octan-6-yl}- 3-methyl- 3H,4H,7H- pyrrolo[2,3-d] pyrimidin- 4-one

SMILES CCn1cc2c(Cl)c(ccc2n1)-c1c[nH]c2nc(N3CCC4(CNC4)C3)n(C)c(=O)c12

InChI Key InChIKey=VFDZZKYBGSPKIS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 685115   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM685115(US12037345, Example 196 | rac-5-(4- chloro-2- ethy...)
Affinity DataIC50: 32nMAssay Description:SHP2 activity was monitored by measuring the conversion of the surrogate substrate 6,8-difluoromethylumbelliferyl phosphate (DiFMUP) to the fluoresce...More data for this Ligand-Target Pair
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Date in BDB:
10/24/2024
Entry Details
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