BDBM685297 2-(3-(6-chloro-2-((1- ((dimethylamino)meth- yl)cyclopro- pyl)methoxy)- 8-fluoro-7-(3-hydroxy- naphthalen-1-yl) quinazolin-4-yl)-3,8- diazabicyclo[3.2.1]oc- tan-1-yl)acetonitrile::US20240239788, Example 36

SMILES CN(C)CC1(COc2nc(N3CC4CCC(CC#N)(C3)N4)c3cc(Cl)c(c(F)c3n2)-c2cc(O)cc3ccccc23)CC1

InChI Key InChIKey=XENFCYDPEKJLGU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 685297   

LigandPNGBDBM685297(US20240239788, Example 36 | 2-(3-(6-chloro-2-((1- ...)
Affinity DataIC50: 5.00E+4nMAssay Description:The RAF-Ras binding domain (RBD) protein interaction assay utilizes recombinant biotinylated KRAS protein containing a G12D mutation (SEQ ID NO: 1) a...More data for this Ligand-Target Pair
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Date in BDB:
10/30/2024
Entry Details
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