BDBM685452 US20240239788, Example 93

SMILES C[C@@]12CC[C@H](CN(C1)c1nc(OCC3(CN4CC[C@@H](F)C4)CC3)nc3CN(CCc13)c1cccc3cccc(Br)c13)N2

InChI Key InChIKey=BAZYGHIEUSFLLT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 685452   

LigandPNGBDBM685452(US20240239788, Example 93)
Affinity DataIC50: 3.53E+4nMAssay Description:The RAF-Ras binding domain (RBD) protein interaction assay utilizes recombinant biotinylated KRAS protein containing a G12D mutation (SEQ ID NO: 1) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent