BDBM686491 Rac-2-(1-((cis)-2-((2-(2,4-dioxo-3- azabicyclo[3.1.1]heptan-1-yl)-1- oxoisoindolin-5- yl)oxy)cyclopentyl)azetidin-3-yl)- 5-fluorobenzonitrile::US20240246935, Example 70

SMILES N#Cc1cc(F)ccc1C1CN([C@@H]2CCC[C@@H]2Oc2ccc3c(c2)CN(C24CC(C2)C(=O)NC4=O)C3=O)C1

InChI Key InChIKey=WAQJMVNBJATBFL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 686491   

TargetProtein cereblon(Human)
Plexium, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 686491BDBM686491(US20240246935, Example 70 | Rac-2-(1-((cis)-2-((2-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent