BDBM686512 Rac-4-(1-((trans)-2-((2-(2,4-dioxo- 3-azabicyclo[3.1.1]heptan-1-yl)-1- oxoisoindolin-5- yl)oxy)cyclohexyl)azetidin-3-yl)- 3-fluorobenzonitrile::US20240246935, Example 91

SMILES N#Cc1ccc(C2CN([C@H]3CCCC[C@@H]3Oc3ccc4c(c3)CN(C35CC(C3)C(=O)NC5=O)C4=O)C2)c(F)c1

InChI Key InChIKey=WGMQQYCYSPXKPN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 686512   

TargetProtein cereblon(Human)
Plexium, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 686512BDBM686512(US20240246935, Example 91 | Rac-4-(1-((trans)-2-((...)
Affinity DataEC50: >1.00E+4nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent