BDBM687377 US20240246964, Compound 398

SMILES COc1cc(ccc1CN1CC2(C1)CCC(=O)N2)-c1nccc(c1Cl)-c1cccc(c1Cl)-c1ccc(CN2CC3(C2)CCC(=O)N3)c(OC)n1

InChI Key InChIKey=KYHXOEJFYPWTMU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 687377   

TargetProgrammed cell death 1 ligand 1(Human)
Arbutus Biopharma

US Patent
LigandPNGBDBM687377(US20240246964, Compound 398)
Affinity DataIC50: 0.278nMAssay Description:PD-L1 His protein was prepared and added at the final concentration of 6 nM in the White opaque 384 well plate (Corning cat #3824BC). PD-L1 small mol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent