BDBM688744 (2S)-2-amino-N-(1-{[((2R)-3-(benzoxy)-1-{1-methansulfonyl-1,2-dihydrospiro[indol-3,4-piperidin]-1-yl}-1-oxopropan-2-yl]carbamoyl}-1-methylethyl)glutaramide::US20240190875, Example 1

SMILES CC(C)(NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@H](COCc1ccccc1)C(=O)N1CCC2(CN(c3ccccc23)S(C)(=O)=O)CC1

InChI Key InChIKey=ZZUDTIXHTAMSKN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 688744   

TargetGrowth hormone secretagogue receptor type 1(Human)
Changchun Genescience Pharmaceutical Co.

US Patent
LigandPNGBDBM688744(US20240190875, Example 1 | (2S)-2-amino-N-(1-{[((2...)
Affinity DataEC50:  15.6nMAssay Description:This method was used to determine the agonism effect of the compound of the invention on the activity of human GHSR protein expressed in human GHSR/C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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