BDBM690254 US20240262826, Compound 199::methyl 3-(5-(3-(5-(2-hydroxyethoxy)pyrazolo[1,5-a]pyridine-3-carboxamido)-4-methylphenyl)-2H-tetrazol-2-yl)azetidine-1-carboxylate

SMILES COC(=O)N1CC(C1)n1nnc(n1)-c1ccc(C)c(NC(=O)c2cnn3ccc(OCCO)cc23)c1

InChI Key InChIKey=LRZYVOWXELPMBQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 690254   

TargetMast/stem cell growth factor receptor Kit(Human)
Blueprint Medicines

US Patent
LigandPNGBDBM690254(methyl 3-(5-(3-(5-(2-hydroxyethoxy)pyrazolo[1,5-a]...)
Affinity DataIC50: 29.6nMAssay Description:For the PathScan phospho c-kit (Tyr719) sandwich ELISA: M-07e cells were resuspended at 2×106 cells/mL in phenol red free, serum-free, GM-CSF-free Is...More data for this Ligand-Target Pair
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Date in BDB:
11/25/2024
Entry Details
US Patent