BDBM691385 US20240277852, Compound 4

SMILES NS(=O)(=O)c1ccc(Nc2ncc(Cl)c(n2)-c2cccc(c2)-c2ccccc2)cc1

InChI Key InChIKey=CZIYACFTBMLEAN-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 691385   

TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM691385(US20240277852, Compound 4)
Affinity DataKd:  64nMAssay Description:The inhibitory activity of the compounds were evaluated using KINOMEscan PIP5K2B (also known as PIP4K2B) and KINOMEscan PIP5K2C (also known as PIP4k2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM691385(US20240277852, Compound 4)
Affinity DataKd: >1.00E+4nMAssay Description:The inhibitory activity of the compounds were evaluated using KINOMEscan PIP5K2B (also known as PIP4K2B) and KINOMEscan PIP5K2C (also known as PIP4k2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 alpha(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM691385(US20240277852, Compound 4)
Affinity DataIC50: 1.00E+4nMAssay Description:The inhibitory activity of the compounds were evaluated using KINOMEscan PIP5K2B (also known as PIP4K2B) and KINOMEscan PIP5K2C (also known as PIP4k2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent