BDBM691399 US20240277852, Compound 56

SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2(F)CC2)C(C)(C)C)c(OCCCCCCC(=O)N2CCC3(CCN(C3=O)c3cncc(Nc4ncc(Cl)c(n4)-c4cccc(c4)-c4ccccc4)c3)CC2)c1

InChI Key InChIKey=VCOSWEBKUXOFPA-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 691399   

TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM691399(US20240277852, Compound 56)
Affinity DataKd:  620nMAssay Description:The inhibitory activity of the compounds were evaluated using KINOMEscan PIP5K2B (also known as PIP4K2B) and KINOMEscan PIP5K2C (also known as PIP4k2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM691399(US20240277852, Compound 56)
Affinity DataKd: >1.00E+4nMAssay Description:The inhibitory activity of the compounds were evaluated using KINOMEscan PIP5K2B (also known as PIP4K2B) and KINOMEscan PIP5K2C (also known as PIP4k2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent