BDBM691504 US20240277683, Example 125

SMILES CCc1cccc(OC)c1S(=O)(=O)Nc1cc(-c2ccc(OC)c(OC)c2)[nH]n1

InChI Key InChIKey=GUWLMGWCCYOVNA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 691504   

LigandChemical structure of BindingDB Monomer ID 691504BDBM691504(US20240277683, Example 125)
Affinity DataIC50: 5.41E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT7(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 691504BDBM691504(US20240277683, Example 125)
Affinity DataIC50: 8.62E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 691504BDBM691504(US20240277683, Example 125)
Affinity DataIC50: 1.25E+5nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent