BDBM691735 4-(difluoromethyl)benzyl (4-(pyridin-4- ylmethyl)phenyl)carbamate::US20240279215, Compound 196

SMILES FC(F)c1ccc(COC(=O)Nc2ccc(Cc3ccncc3)cc2)cc1

InChI Key InChIKey=SRDRCDKWGXFQSH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 691735   

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandPNGBDBM691735(US20240279215, Compound 196 | 4-(difluoromethyl)be...)
Affinity DataEC50:  7.22E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
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Date in BDB:
11/26/2024
Entry Details
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