BDBM691808 US20240279215, Compound 269::oxazol-5-ylmethyl (4-(2- (4-(oxetan-3- yl)piperazin-1- yl)ethyl)phenyl)carbamate

SMILES O=C(Nc1ccc(CCN2CCN(CC2)C2COC2)cc1)OCc1cnco1

InChI Key InChIKey=UGKOTFVEKNRMJO-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 691808   

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandPNGBDBM691808(US20240279215, Compound 269 | oxazol-5-ylmethyl (4...)
Affinity DataEC50:  4.41E+4nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
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Date in BDB:
11/26/2024
Entry Details
US Patent