BDBM691937 US20240279215, Compound 398::oxazol-5-ylmethyl (4-((2- (dimethylcarbamoyl)-2- azaspiro[3.3]heptan-6- yl)methyl)-3- fluorophenyl)carbamate

SMILES CN(C)C(=O)N1CC2(CC(Cc3ccc(NC(=O)OCc4cnco4)cc3F)C2)C1

InChI Key InChIKey=KXVSSCIXVJLEOR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 691937   

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandPNGBDBM691937(US20240279215, Compound 398 | oxazol-5-ylmethyl (4...)
Affinity DataEC50:  3.29E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
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Date in BDB:
11/26/2024
Entry Details
US Patent