BDBM693288 1-phenyl-N-(2,3,6-trifluoro-4-((3-(2- (piperidin-3-ylmethyl)pyrimidin-4- yl)pyridin-2- yl)oxy)phenyl)methanesulfonamide::US12071425, Compound 198::US12071425, Compound 199

SMILES Fc1cc(Oc2ncccc2-c2ccnc(CC3CCCNC3)n2)c(F)c(F)c1NS(=O)(=O)Cc1ccccc1

InChI Key InChIKey=FZZLPAWFJYREKU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 693288   

LigandPNGBDBM693288(US12071425, Compound 199 | 1-phenyl-N-(2,3,6-trifl...)
Affinity DataIC50: 110nMAssay Description:To determine the affinity of compound binding to the kinase domain of IRE1 alpha, a Time Resolved Fluorescence Resonance Energy Transfer (TR-FRET) co...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/6/2024
Entry Details
US Patent

LigandPNGBDBM693288(US12071425, Compound 199 | 1-phenyl-N-(2,3,6-trifl...)
Affinity DataIC50: 1.30E+3nMAssay Description:To determine the affinity of compound binding to the kinase domain of IRE1 alpha, a Time Resolved Fluorescence Resonance Energy Transfer (TR-FRET) co...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/6/2024
Entry Details
US Patent