BDBM695981 (S)-6-((5-azaspiro[2.4]heptan-5- yl)methyl)-2-cyclopropyl-N-(3-(3- (fluoro(4-methyl-4H-1,2,4-triazol-3- yl)methyl)oxetan-3- yl)phenyl)pyrimidine-4-carboxamide::US20240300927, Compound 63

SMILES Cn1cnnc1[C@@H](F)C1(COC1)c1cccc(NC(=O)c2cc(CN3CCC4(CC4)C3)nc(n2)C2CC2)c1

InChI Key InChIKey=VPDLXUZRAXKLDC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 695981   

LigandChemical structure of BindingDB Monomer ID 695981BDBM695981(US20240300927, Compound 63 | (S)-6-((5-azaspiro[2....)
Affinity DataIC50: 170nMAssay Description:Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 concentrat...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/8/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 695981BDBM695981(US20240300927, Compound 63 | (S)-6-((5-azaspiro[2....)
Affinity DataIC50: 180nMAssay Description:Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 concentrat...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/8/2025
Entry Details
US Patent